Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9507465 | 0.94 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1 | |
| SCHEMBL9503926 | 0.81 | CYSLTR2 (0.37) | CYSLTR2CYSLTR1 | |
| SCHEMBL9560824 | 0.79 | CYSLTR2 (0.72) | CYSLTR2CYSLTR1 | |
| SCHEMBL9559948 | 0.79 | CYSLTR2 (0.72) | CYSLTR2CYSLTR1 | |
| SCHEMBL9560059 | 0.79 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1 | |
| SCHEMBL9430241 | 0.74 | CYSLTR2 (0.67) | CYSLTR2CYSLTR1 | |
| SCHEMBL9503905 | 0.74 | CYSLTR2 (0.67) | CYSLTR2CYSLTR1 | |
| Pobilukast SCHEMBL29473536 | 0.73 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1 | |
| Pobilukast SCHEMBL125952 | 0.73 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1 | |
| Pobilukast SCHEMBL6437479 | 0.73 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375348-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-06-23 | — | — | EP | claimed |
| EP-0375348-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-06-23 | — | — | EP | disclosed |
| EP-0375348-A1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1990-06-27 | — | — | EP | disclosed |