Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8422160 | 0.89 | TSHR (0.55) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL5696148 | 0.88 | TSHR (0.53) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| Acrylic Acid Methyl Ester SCHEMBL27859782 | 0.76 | TSHR (0.59) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL21341700 | 0.73 | TSHR (0.51) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL95157 | 0.73 | TSHR (0.64) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL4076455 | 0.72 | TSHR (0.59) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| Hydrochloric Acid SCHEMBL9139239 | 0.72 | KDM4E (0.52) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL8437347 | 0.72 | ADRB2 (0.54) | TSHRADRB2ADRB1ADRB3 | |
| Acrylic Acid Methyl Ester SCHEMBL27651161 | 0.71 | TSHR (0.53) | TSHRALDH1A1HPGDTP53HIF1A | |
| SCHEMBL19757343 | 0.71 | TSHR (0.53) | TSHRALDH1A1HPGDTP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187281-B1 | NOVEL CARBOXYLATE POLYMERS AND PROCESSES FOR THEIR PREPARATION AND USE | RHONE-POULENC SPECIALTY CHEMICALS CO. (US) | 1993-06-23 | — | — | EP | claimed |
| US-4808668-A | SEWAGE TREATMENT FLOCCULANT | ALLIED-SIGNAL INC. (US) | 1989-02-28 | — | — | US | claimed |
| EP-0187281-A2 | Novel carboxylate polymers and processes for their preparation and use | RHONE-POULENC SPECIALTY CHEMICALS CO. (US) | 1986-07-16 | — | — | EP | claimed |