Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503879 | 0.98 | TSHR (0.48) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL9503575 | 0.91 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| Hydrochloric Acid SCHEMBL6931227 | 0.81 | MAPT (0.32) | SMN1; SMN2MAPTGALR3BLM | |
| Hydrochloric Acid SCHEMBL15155490 | 0.79 | TSHR (0.48) | TSHRHPGDALDH1A1TP53HIF1A | |
| Hydrochloric Acid SCHEMBL600420 | 0.78 | TSHR (0.47) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL27336395 | 0.77 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| Hydrochloric Acid SCHEMBL28987031 | 0.77 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| Hydrochloric Acid SCHEMBL2398907 | 0.76 | TSHR (0.46) | TSHRHPGDALDH1A1TP53HIF1A | |
| Hydrochloric Acid SCHEMBL4814402 | 0.76 | TSHR (0.47) | TSHRALDH1A1SMN1; SMN2THRBMAPT | |
| Hydrochloric Acid SCHEMBL27760619 | 0.76 | TSHR (0.55) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997535-A | A kind of high-early strength type polycarboxylic acids dehydragent and preparation method thereof | 河北三楷深发科技股份有限公司 | 2018-12-14 | — | — | CN | claimed |
| CN-101560005-B | Amphoteric polymeric flocculant for removing phosphor in sewage | UNIV HUNAN NORMAL | 2011-01-05 | — | — | CN | claimed |
| CN-101560005-A | Amphoteric polymeric flocculant for removing phosphor in sewage | UNIV HUNAN NORMAL (CN) | 2009-10-21 | — | — | CN | claimed |
| US-12157972-B2 | Textile printing ink | Konica Minolta, Inc. (JP) | 2024-12-03 | — | — | US | disclosed |
| CN-118289956-A | Method for removing hydroxamic acid in hydroxamic acid-containing compound flotation wastewater | 有研资源环境技术研究院(北京)有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-116133865-A | Aqueous inkjet ink and method for printing fiber structure by inkjet method | 山阳色素株式会社 | 2023-05-16 | — | — | CN | disclosed |
| EP-4123088-A1 | TEXTILE PRINTING INK | KONICA MINOLTA, INC. (JP) | 2023-01-25 | — | — | EP | disclosed |
| US-20230002967-A1 | TEXTILE PRINTING INK | Konica Minolta, Inc. (JP) | 2023-01-05 | — | — | US | disclosed |
| EP-3988712-A1 | INKJET TEXTILE PRINTING INK AND IMAGE FORMING METHOD | KONICA MINOLTA, INC. (JP) | 2022-04-27 | — | — | EP | disclosed |
| CN-108997535-A | A kind of high-early strength type polycarboxylic acids dehydragent and preparation method thereof | 河北三楷深发科技股份有限公司 | 2018-12-14 | — | — | CN | disclosed |
| CN-101560005-B | Amphoteric polymeric flocculant for removing phosphor in sewage | UNIV HUNAN NORMAL | 2011-01-05 | — | — | CN | disclosed |
| CN-101560005-A | Amphoteric polymeric flocculant for removing phosphor in sewage | UNIV HUNAN NORMAL (CN) | 2009-10-21 | — | — | CN | disclosed |
| EP-0187281-B1 | NOVEL CARBOXYLATE POLYMERS AND PROCESSES FOR THEIR PREPARATION AND USE | RHONE-POULENC SPECIALTY CHEMICALS CO. (US) | 1993-06-23 | — | — | EP | disclosed |
| US-4808668-A | SEWAGE TREATMENT FLOCCULANT | ALLIED-SIGNAL INC. (US) | 1989-02-28 | — | — | US | disclosed |
| EP-0187281-A2 | Novel carboxylate polymers and processes for their preparation and use | RHONE-POULENC SPECIALTY CHEMICALS CO. (US) | 1986-07-16 | — | — | EP | disclosed |