Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9507169 | 0.92 | KDM4E (0.40) | KDM4EMAPTSLC22A2SLC22A1PGR | |
| SCHEMBL9503390 | 0.85 | KDM4E (0.41) | KDM4EMAPTSLC22A2SLC22A1PGR | |
| SCHEMBL9507126 | 0.72 | SMN1; SMN2 (0.44) | KDM4EMAPTMEN1KMT2ANPC1 | |
| SCHEMBL9505436 | 0.72 | SMN1; SMN2 (0.44) | KDM4EMAPTMEN1KMT2ANPC1 | |
| SCHEMBL9505474 | 0.72 | KEAP1 (0.39) | KDM4EMAPTMEN1KMT2ANPC1 | |
| SCHEMBL9503407 | 0.71 | SMN1; SMN2 (0.43) | KDM4ESLC22A2SLC22A1PGRTHRB | |
| SCHEMBL9503387 | 0.70 | SMN1; SMN2 (0.45) | KDM4ESLC22A2SLC22A1PGRTHRB | |
| SCHEMBL10856206 | 0.69 | KDM4E (0.42) | KDM4EKCNH2CYP3A4TSHRMEN1 | |
| SCHEMBL9503672 | 0.69 | MEN1 (0.43) | KDM4ESLC22A2SLC22A1PGRTHRB | |
| SCHEMBL9507165 | 0.68 | MEN1 (0.43) | KDM4EMEN1KMT2ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0336561-B1 | 2-PYRIDYLACETIC ACID DERIVATIVES, PREPARATIONS THEREOF, AND COMPOSITIONS CONTAINING THEM | SUNTORY LIMITED (JP) | 1993-07-28 | — | — | EP | claimed |