Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503389 | 0.84 | MAPT (0.37) | KEAP1NFE2L2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3689611 | 0.78 | P2RX7 (0.35) | SMN1; SMN2L3MBTL1TRPM8 | |
| SCHEMBL9507126 | 0.77 | SMN1; SMN2 (0.44) | PKMSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL9505436 | 0.77 | SMN1; SMN2 (0.44) | PKMSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL9503407 | 0.75 | SMN1; SMN2 (0.43) | PKMSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL10697581 | 0.75 | KEAP1 (0.43) | KEAP1NFE2L2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9503387 | 0.75 | SMN1; SMN2 (0.45) | PKMSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL6589388 | 0.75 | KEAP1 (0.61) | KEAP1NFE2L2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9503390 | 0.74 | KDM4E (0.41) | PKMSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL16500241 | 0.74 | KEAP1 (0.49) | KEAP1NFE2L2SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0336561-B1 | 2-PYRIDYLACETIC ACID DERIVATIVES, PREPARATIONS THEREOF, AND COMPOSITIONS CONTAINING THEM | SUNTORY LIMITED (JP) | 1993-07-28 | — | — | EP | claimed |