SCHEMBL9503684

SCHEMBL9503684

CO[C@H]1O[C@H](C)[C@H](OCc2ccccc2)[C@@H](OC)[C@H]1F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SSTR1 P30872 1/20 0.42
SSTR2 P30874 1/20 0.42
SSTR4 P31391 1/20 0.42
SSTR3 P32745 1/20 0.42
SSTR5 P35346 1/20 0.42
BCHE P06276 2/20 0.40
GJB2 P29033 1/20 0.37
PDPK1 O15530 1/20 0.36
MTOR P42345 1/20 0.36
MAPT P10636 1/20 0.36
CYP2C19 P33261 1/20 0.36
LGALS8 O00214 1/20 0.34
PSEN1 P49768 3/20 0.34
PSEN2 P49810 3/20 0.34
APH1B Q8WW43 3/20 0.34
NCSTN Q92542 3/20 0.34
APH1A Q96BI3 3/20 0.34
PSENEN Q9NZ42 3/20 0.34
PTPN2 P17706 1/20 0.34
PTPN1 P18031 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7892063 1.00 SSTR1 (0.42) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL7892058 0.88 SSTR5 (0.41) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL9503678 0.88 SSTR5 (0.41) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL7899774 0.87 PDPK1 (0.39) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL8401248 0.87 SSTR1 (0.50) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL6878433 0.87 SSTR1 (0.52) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL6878426 0.87 SSTR1 (0.52) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL25362771 0.85 SSTR1 (0.54) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL20107395 0.85 SSTR1 (0.54) SSTR1SSTR2SSTR4SSTR3SSTR5
SCHEMBL18573699 0.85 SSTR1 (0.54) SSTR1SSTR2SSTR4SSTR3SSTR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0230322-B1 2,6-DIDEOXY-2-FLUORO-L-TALOPYRANOSE AND DERIVATES THEREOF AND THE PRODUCTION OF THESE COMPOUNDS ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1993-07-21 EP disclosed
EP-0230013-B1 NEW ANTHRACYCLINE DERIVATIVES, USES THEREOF AS ANTITUMOR AGENT AND PRODUCTION THEREOF ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1992-06-17 EP disclosed
US-5034517-A Process for producing 2,6-dideoxy-2-fluoro-L-talopyranose ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1991-07-23 US disclosed
EP-0230322-A2 2,6-Dideoxy-2-fluoro-L-talopyranose and derivates thereof and the production of these compounds ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1987-07-29 EP disclosed
EP-0230013-A1 New anthracycline derivatives, uses thereof as antitumor agent and production thereof ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1987-07-29 EP disclosed