SCHEMBL9503811

SCHEMBL9503811

CNC(=S)n1nccc1C

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.35
KDM4E B2RXH2 1/20 0.35
POLB P06746 1/20 0.35
ALDH1A1 P00352 3/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
MAPK1 P28482 1/20 0.33
LMNA P02545 2/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9507827 0.76 ALDH1A1 (0.42) KDM4EPOLBALDH1A1MAPK1LMNA
SCHEMBL4870074 0.75
SCHEMBL4305449 0.73 FBP1 (0.36) ALDH1A1MAPK1
SCHEMBL14385409 0.70 ALDH1A1 (0.47) KDM4EALDH1A1MAPK1LMNA
SCHEMBL2652518 0.68
SCHEMBL21241066 0.68
SCHEMBL21233056 0.68
SCHEMBL12635474 0.67
SCHEMBL9043574 0.63 ALDH1A1 (0.56) KDM4EPOLBALDH1A1MEN1KMT2A
SCHEMBL22779334 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0547055-A1 AGENTS FOR INCREASING BIOMASS PRODUCTION SKW STICKSTOFFWERKE PIESTERITZ GmbH (DE) 1993-06-23 EP claimed
WO-1991018509-A1 AGENTS FOR INCREASING BIOMASS PRODUCTION STICKSTOFFWERKE AG WITTENBERG-PIESTERITZ (DE) 1991-12-12 WO claimed
EP-0547055-A1 AGENTS FOR INCREASING BIOMASS PRODUCTION SKW STICKSTOFFWERKE PIESTERITZ GmbH (DE) 1993-06-23 EP disclosed
WO-1991018509-A1 AGENTS FOR INCREASING BIOMASS PRODUCTION STICKSTOFFWERKE AG WITTENBERG-PIESTERITZ (DE) 1991-12-12 WO disclosed