Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2984733 | 0.81 | — | — | |
| SCHEMBL19978884 | 0.79 | PDPK1 (0.36) | PDPK1CYP1A2CYP2C19DYRK1AABL1 | |
| SCHEMBL22700363 | 0.79 | MEN1 (0.37) | PDPK1CYP1A2CYP2C19MEN1CSNK2A2 | |
| Methylguanine SCHEMBL1336757 | 0.79 | CDK1 (0.41) | PDPK1 | |
| SCHEMBL1443986 | 0.79 | XDH (0.37) | PDPK1CYP1A2CYP2C19CSNK2A1ABL1 | |
| SCHEMBL31380770 | 0.79 | XDH (0.37) | PDPK1CYP1A2CYP2C19CSNK2A1ABL1 | |
| SCHEMBL18961720 | 0.76 | GAA (0.35) | PDPK1CYP1A2CYP2C19KMT2ALMNA | |
| SCHEMBL9465638 | 0.76 | PDPK1 (0.34) | PDPK1MEN1CSNK2A2RAB9ACSNK2B | |
| Xanthine SCHEMBL918381 | 0.75 | MEN1 (0.34) | MEN1CSNK2A2RAB9ACSNK2BCSNK2A1 | |
| Xanthine SCHEMBL9443796 | 0.75 | MEN1 (0.34) | MEN1CSNK2A2RAB9ACSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012154321-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VIRAL INFECTIONS | IDENIX PHARMACEUTICALS, INC. (US) | 2012-11-15 | — | — | WO | disclosed |
| WO-2011123586-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VIRAL INFECTIONS | IDENIX PHARMACEUTICALS, INC. (US) | 2011-10-06 | — | — | WO | disclosed |
| EP-0539487-A1 | ANTIVIRAL PHOSPHONO-ALKEN DERIVATIVES OF PURINES | BEECHAM GROUP PLC (GB) | 1993-05-05 | — | — | EP | disclosed |
| WO-1992001698-A1 | ANTIVIRAL PHOSPHONO-ALKEN DERIVATIVES OF PURINES | BEECHAM GROUP PLC (GB) | 1992-02-06 | — | — | WO | disclosed |