SCHEMBL9503837

SCHEMBL9503837

CCCCCCCCCCCOc1ccc(NC(N)=O)cc1

nearest known ligand 0.69

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.69
FAAH O00519 14/20 0.67
S1PR1 P21453 4/20 0.64
S1PR3 Q99500 4/20 0.64
GAA P10253 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7759451 1.00 ALDH1A1 (0.69) ALDH1A1FAAHS1PR1S1PR3GAA
SCHEMBL23554170 1.00 ALDH1A1 (0.69) ALDH1A1FAAHS1PR1S1PR3GAA
SCHEMBL5530025 1.00 ALDH1A1 (0.69) ALDH1A1FAAHS1PR1S1PR3GAA
SCHEMBL6831704 0.95 ALDH1A1 (0.75) ALDH1A1FAAHGAAL3MBTL1
SCHEMBL27182821 0.89 ALDH1A1 (0.75) ALDH1A1FAAH
SCHEMBL9014684 0.88 FAAH (0.61) FAAHS1PR1S1PR3GAAL3MBTL1
SCHEMBL9014848 0.88 FAAH (0.61) FAAHS1PR1S1PR3GAAL3MBTL1
SCHEMBL9014657 0.86 FAAH (0.58) FAAHS1PR1S1PR3GAAL3MBTL1
SCHEMBL9014856 0.86 FAAH (0.58) FAAHS1PR1S1PR3GAAL3MBTL1
SCHEMBL5218334 0.86 FAAH (0.70) FAAHS1PR1S1PR3GAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0543891-A1 DIPHENYLUREA DERIVATIVES RHONE-POULENC RORER LIMITED (GB) 1993-06-02 EP disclosed
WO-1992003413-A1 DIPHENYLUREA DERIVATIVES RHONE-POULENC RORER LIMITED (GB) 1992-03-05 WO disclosed