SCHEMBL9503901

SCHEMBL9503901

Cc1c(Br)c(O)c(Br)c(C)c1-c1c(C)c(Br)c(O)c(Br)c1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
HPGD P15428 2/20 0.47
ALOX15 P16050 2/20 0.47
HIF1A Q16665 2/20 0.47
HSD17B10 Q99714 2/20 0.47
RECQL P46063 2/20 0.47
MAPK1 P28482 1/20 0.47
TP53 P04637 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
ALOX12 P18054 1/20 0.44
CYP2C19 P33261 1/20 0.44
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
KDM4E B2RXH2 1/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13964596 0.83 ALDH1A1 (0.50) ALDH1A1HPGDALOX15HIF1AHSD17B10
SCHEMBL13964614 0.83 ALDH1A1 (0.50) ALDH1A1HPGDALOX15HIF1AHSD17B10
SCHEMBL6377646 0.83 ALDH1A1 (0.50) ALDH1A1HPGDALOX15HIF1AHSD17B10
SCHEMBL13964598 0.80 ALDH1A1 (0.56) ALDH1A1HPGDALOX15HIF1AHSD17B10
SCHEMBL9503616 0.79 MAPT (0.36) ALDH1A1HPGDALOX15HIF1AHSD17B10
SCHEMBL11682268 0.79 CA1 (0.53) ALDH1A1HPGDALOX15HIF1AHSD17B10
SCHEMBL6115897 0.79 ALDH1A1 (0.62) ALDH1A1HPGDALOX15HIF1AHSD17B10
SCHEMBL3418208 0.78 ALDH1A1 (0.62) ALDH1A1HPGDALOX15HIF1AHSD17B10
SCHEMBL13964610 0.78 ALDH1A1 (0.48) ALDH1A1HPGDALOX15HIF1AHSD17B10
SCHEMBL3168640 0.76 ALDH1A1 (0.60) ALDH1A1HPGDALOX15HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0260571-B1 HALOGENATED EPOXY RESINS AND ADVANCED RESINS PREPARED THEREFROM THE DOW CHEMICAL COMPANY (US) 1993-06-30 EP claimed
EP-0239784-B1 CURABLE COMPOSITIONS CONTAINING A POLYEPOXIDE AND A HALOGENATED BISPHENOL THE DOW CHEMICAL COMPANY (US) 1992-05-06 EP claimed
US-4783363-A ELECTRICAL LAMINATES THE DOW CHEMICAL COMPANY (US) 1988-11-08 US claimed
EP-0260571-B1 HALOGENATED EPOXY RESINS AND ADVANCED RESINS PREPARED THEREFROM THE DOW CHEMICAL COMPANY (US) 1993-06-30 EP disclosed
EP-0239784-B1 CURABLE COMPOSITIONS CONTAINING A POLYEPOXIDE AND A HALOGENATED BISPHENOL THE DOW CHEMICAL COMPANY (US) 1992-05-06 EP disclosed
US-4895755-A ENCAPSULATION OF ELECTRONIC COMPONENTS THE DOW CHEMICAL COMPANY (US) 1990-01-23 US disclosed
US-4783363-A ELECTRICAL LAMINATES THE DOW CHEMICAL COMPANY (US) 1988-11-08 US disclosed
US-4783363-A ELECTRICAL LAMINATES THE DOW CHEMICAL COMPANY (US) 1988-11-08 US disclosed
WO-1988002012-A1 HALOGENATED EPOXY RESINS AND ADVANCED RESINS PREPARED THEREFROM THE DOW CHEMICAL COMPANY (US) 1988-03-24 WO disclosed
US-4727119-A HALOGEN ATOM IN META POSITION WITH RESPECT TO GLYCIDYL ETHER ENCAPSULATION ELECTRICAL COMPONENTS THE DOW CHEMICAL COMPANY (US) 1988-02-23 US disclosed
US-4058570-A FROM BROMINE AND A TETRASUBSTITUTED DIPHENOQUINONE GENERAL ELECTRIC COMPANY (US) 1977-11-15 US disclosed