Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502274 | 0.99 | ACAT1 (0.42) | ACAT1NAMPTHDAC3HDAC1NPC1 | |
| SCHEMBL9506172 | 0.92 | ACAT1 (0.49) | ACAT1NAMPTHDAC3HDAC1NPC1 | |
| SCHEMBL9504006 | 0.92 | ACAT1 (0.49) | ACAT1NAMPTHDAC3HDAC1NPC1 | |
| SCHEMBL9503861 | 0.88 | HDAC3 (0.45) | ACAT1NAMPTHDAC3HDAC1NPC1 | |
| SCHEMBL9502911 | 0.87 | ACAT1 (0.45) | ACAT1NAMPTHDAC3HDAC1NPC1 | |
| SCHEMBL9503199 | 0.85 | HPGD (0.47) | ACAT1NAMPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL9505632 | 0.85 | ACAT1 (0.51) | ACAT1L3MBTL1SMN1; SMN2HPGDNAAA | |
| SCHEMBL9503112 | 0.85 | ACAT1 (0.51) | ACAT1L3MBTL1SMN1; SMN2HPGDNAAA | |
| SCHEMBL9505636 | 0.84 | ACAT1 (0.45) | ACAT1NAMPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL9504110 | 0.83 | ACAT1 (0.59) | ACAT1NAMPTHDAC3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543865-A1 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003412-A2 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |