Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9088375 | 0.86 | TYMS (0.79) | DHFRTYMS | |
| SCHEMBL31490169 | 0.86 | DHFR (0.87) | DHFRTYMS | |
| SCHEMBL7263046 | 0.86 | DHFR (0.87) | DHFRTYMS | |
| SCHEMBL9502537 | 0.84 | DHFR (0.67) | DHFRTYMS | |
| SCHEMBL9555952 | 0.84 | DHFR (0.76) | DHFRTYMS | |
| SCHEMBL9300016 | 0.80 | DHFR (0.62) | DHFRTYMS | |
| SCHEMBL9823308 | 0.80 | DHFR (1.00) | DHFRTYMS | |
| SCHEMBL9252778 | 0.79 | TYMS (0.68) | TYMS | |
| SCHEMBL9823269 | 0.79 | DHFR (1.00) | DHFRTYMS | |
| SCHEMBL9823412 | 0.79 | DHFR (1.00) | DHFRTYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252573-A | Quinazoline derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-10-12 | — | — | US | disclosed |