Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9427781 | 0.89 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2TP53PDE10A | |
| SCHEMBL9584450 | 0.89 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2TP53ALOX5 | |
| SCHEMBL9584634 | 0.81 | ALOX5 (0.64) | ALOX5 | |
| SCHEMBL9507030 | 0.81 | ALOX5 (0.64) | ALOX5 | |
| Water SCHEMBL9588688 | 0.80 | ALOX5 (0.63) | ALOX5 | |
| SCHEMBL9505365 | 0.78 | NPC1 (0.51) | RAB9ANPC1SMN1; SMN2ALOX5MAPT | |
| SCHEMBL13696704 | 0.78 | NPC1 (0.51) | RAB9ANPC1SMN1; SMN2ALOX5MAPT | |
| SCHEMBL9503959 | 0.77 | NPC1 (0.50) | RAB9ANPC1SMN1; SMN2ALOX5MAPT | |
| Water SCHEMBL9427943 | 0.76 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2TP53PDE10A | |
| SCHEMBL9427541 | 0.76 | NPC1 (0.51) | RAB9ANPC1SMN1; SMN2TP53PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0547148-A1 | NAPHTHALENEPROPIONIC ACID DERIVATIVES AS ANTI-INFLAMMATORY/ANTIALLERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-06-23 | — | — | EP | claimed |
| WO-1992004325-A1 | NAPHTHALENEPROPIONIC ACID DERIVATIVES AS ANTI-INFLAMMATORY/ANTIALLERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-03-19 | — | — | WO | claimed |
| US-5208344-A | Benzothiazole derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-05-04 | — | — | US | disclosed |