SCHEMBL9504077

SCHEMBL9504077

Clc1[c]cc(-c2ccccc2)[c]c1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.37
ALDH1A1 P00352 3/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HPGD P15428 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CYP2A6 P11509 1/20 0.34
TSHR P16473 1/20 0.32
RAB9A P51151 1/20 0.31
KDM4E B2RXH2 2/20 0.31
HSP90AA1 P07900 1/20 0.31
HSP90AB1 P08238 1/20 0.31
LMNA P02545 1/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5047733 0.85 ALDH1A1 (0.47) CYP1A2ALDH1A1MEN1KMT2AHPGD
SCHEMBL458242 0.74 CYP1A2 (0.50) CYP1A2ALDH1A1MEN1KMT2AHPGD
SCHEMBL358614 0.73 CYP1A2 (0.48) CYP1A2ALDH1A1MEN1KMT2AHPGD
SCHEMBL3713009 0.71
SCHEMBL2958548 0.67 ALDH1A1 (0.45) CYP1A2ALDH1A1SMN1; SMN2CYP2A6TSHR
SCHEMBL2448169 0.67 ALDH1A1 (0.45) CYP1A2ALDH1A1SMN1; SMN2CYP2A6TSHR
Benzene SCHEMBL8005678 0.65 TSHR (0.38) CYP1A2CYP2A6TSHRLMNA
SCHEMBL21295702 0.65 LDHA (0.40) MEN1KMT2ASMN1; SMN2RAB9A
SCHEMBL6437984 0.65 CYP1A2 (0.39) CYP1A2ALDH1A1MEN1KMT2AHPGD
SCHEMBL608940 0.65 ALDH1A1 (0.36) ALDH1A1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0262900-B1 ANISOTROPIC MELT POLYESTERS WITH IMPROVED GLASS TRANSITION TEMPERATURE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-06-16 EP claimed