Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 11/20 | 0.58 |
| ▸ | MMP3 | P08254 | 9/20 | 0.50 |
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504076 | 1.00 | MMP1 (0.58) | MMP1MMP3MMP2 | |
| SCHEMBL9503311 | 0.88 | MMP3 (0.62) | MMP1MMP3MMP2 | |
| SCHEMBL9503299 | 0.88 | MMP3 (0.62) | MMP1MMP3MMP2 | |
| SCHEMBL9503126 | 0.84 | MMP1 (0.55) | MMP1MMP3MMP2 | |
| SCHEMBL9503152 | 0.84 | MMP1 (0.55) | MMP1MMP3MMP2 | |
| SCHEMBL10715152 | 0.83 | MMP1 (0.41) | MMP1MMP3MMP2 | |
| SCHEMBL9506233 | 0.82 | MMP3 (0.71) | MMP1MMP3MMP2 | |
| SCHEMBL9506251 | 0.82 | MMP3 (0.71) | MMP1MMP3MMP2 | |
| SCHEMBL9790846 | 0.79 | MMP3 (0.60) | MMP1MMP3MMP2 | |
| SCHEMBL9790866 | 0.79 | MMP3 (0.60) | MMP1MMP3MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276436-B1 | PHOSPHINIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-06-16 | — | — | EP | disclosed |
| US-5006651-A | Rheumatic diseases, bone disorders | HOFFMAN-LA ROCHE INC. (US) | 1991-04-09 | — | — | US | disclosed |
| US-4885283-A | Phosphinic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1989-12-05 | — | — | US | disclosed |