SCHEMBL9504120

SCHEMBL9504120

O=C1c2ccccc2C(=O)c2c(Sc3ccccc3)c(Sc3ccccc3)c(Sc3ccccc3)c(Sc3ccccc3)c21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.58
MEN1 O00255 6/20 0.58
KMT2A Q03164 6/20 0.58
ALDH1A1 P00352 4/20 0.58
ADORA2A P29274 3/20 0.53
KDM4E B2RXH2 3/20 0.52
MAPK1 P28482 2/20 0.52
NSD2 O96028 1/20 0.52
CDC25B P30305 3/20 0.47
CDC25A P30304 2/20 0.47
PTPN1 P18031 1/20 0.47
NPSR1 Q6W5P4 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
HKDC1 Q2TB90 1/20 0.44
MAOA P21397 3/20 0.43
FGR P09769 1/20 0.43
PIM1 P11309 1/20 0.43
CSNK1A1 P48729 1/20 0.43
CSNK1D P48730 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10355980 0.86 ADORA2A (0.60) MAPTMEN1KMT2AALDH1A1ADORA2A
SCHEMBL14580985 0.79 MAPT (0.67) MAPTMEN1KMT2AALDH1A1ADORA2A
SCHEMBL1038701 0.78 ALDH1A1 (0.66) MAPTMEN1KMT2AALDH1A1ADORA2A
SCHEMBL11003012 0.77 ALDH1A1 (0.40) MAPTMEN1KMT2AALDH1A1ADORA2A
SCHEMBL8723876 0.76 HPGD (0.53) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL10502055 0.76 MAPT (0.70) MAPTMEN1KMT2AALDH1A1ADORA2A
SCHEMBL285567 0.75 MAPT (0.89) MAPTMEN1KMT2AALDH1A1ADORA2A
Anthraquinone SCHEMBL11411972 0.75 MAPT (0.89) MAPTMEN1KMT2AALDH1A1ADORA2A
SCHEMBL30475313 0.75 MAPT (0.89) MAPTMEN1KMT2AALDH1A1ADORA2A
SCHEMBL15537555 0.75 MAPT (1.00) MAPTMEN1KMT2AALDH1A1ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0260083-B1 COLOR BALANCED RUBBER-REINFORCED PLASTIC THE DOW CHEMICAL COMPANY (US) 1993-06-30 EP disclosed