Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | MGAM | O43451 | 1/20 | 0.59 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.59 |
| ▸ | SI | P14410 | 1/20 | 0.59 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10617187 | 0.86 | GAA (0.78) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL7267319 | 0.83 | GAA (0.49) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL9518606 | 0.81 | GAA (0.64) | GAAMGAMAMY1ASIMGAM2 | |
| Oxodipine SCHEMBL332244 | 0.80 | GAA (0.91) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL9504280 | 0.79 | KDM4E (0.45) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL7267326 | 0.78 | KDM4E (0.48) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL9505147 | 0.77 | ADRA2A (0.51) | GAAKDM4EHSD17B10ALDH1A1KMT2A | |
| SCHEMBL10617911 | 0.76 | GAA (0.55) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL29663663 | 0.75 | KDM4E (0.78) | GAAKDM4ECYP2C9HSD17B10CYP1A2 | |
| SCHEMBL820019 | 0.75 | KDM4E (0.78) | GAAKDM4ECYP2C9HSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0458823-B1 | A PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE POLYSUBSTITUTED 1,4-DIHYDROPYRIDINES | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1993-10-13 | — | — | EP | disclosed |
| US-5245039-A | PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE POLYSUBSTITUTED 1,4-DIHYDROPYRIDINES | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-09-14 | — | — | US | disclosed |
| EP-0383320-A1 | A process for preparation of enantiomerically pure polysubstituted 1,4-dihydropyridines | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1990-08-22 | — | — | EP | disclosed |