SCHEMBL9504322

SCHEMBL9504322

C=C(C)Cc1ccccc1/C=C/C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER3 P43115 13/20 0.55
PTGER2 P43116 12/20 0.55
PTGER4 P35408 10/20 0.55
PTGDR Q13258 5/20 0.52
TBXA2R P21731 4/20 0.52
PTGER1 P34995 5/20 0.50
PTGFR P43088 3/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
NFKB1 P19838 1/20 0.50
CA4 P22748 1/20 0.50
PTGIR P43119 2/20 0.49
MAPT P10636 1/20 0.47
TBXAS1 P24557 1/20 0.47
HTT P42858 1/20 0.44
HDAC3 O15379 1/20 0.43
TNKS O95271 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC1 Q13547 1/20 0.43
HCAR2 Q8TDS4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8012913 0.83 PTGER3 (0.61) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL8012911 0.83 PTGER3 (0.61) PTGER3PTGER2PTGER4PTGDRTBXA2R
Methacrylic Acid SCHEMBL10714797 0.83 PTGER3 (0.54) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL10872401 0.82 HCAR2 (0.40) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL309761 0.81 PTGER3 (0.63) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL3214322 0.81 PTGER3 (0.63) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL1150939 0.81 PTGER3 (0.63) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL6274122 0.78 PTGER3 (0.63) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL6274118 0.78 PTGER3 (0.63) PTGER3PTGER2PTGER4PTGDRTBXA2R
SCHEMBL3123182 0.77 PTGER3 (0.63) PTGER3PTGER2PTGER4PTGDRTBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0383655-B1 USE OF POLYDIORGANOSILOXANES WITH DIBENZOYLMETHANE FUNCTION IN COSMETICS AND COSMETIC COMPOSITIONS CONTAINING THESE COMPOUNDS FOR THE PROTECTION OF HAIR AND SKIN L'OREAL (FR) 1993-04-28 EP disclosed
EP-0335777-B1 COSMETIC USE OF DIORGANOPOLYSILOXANES BEARING A 3-BENZYLIDENE-CAMPHOR FUNCTIONAL GROUP L'OREAL (FR) 1991-12-18 EP disclosed
US-4562278-A SUNSCREEN AGENTS DOW CORNING, LTD. (GB) 1985-12-31 US disclosed
US-4558111-A Method for preparing acrylic functional halosilanes and halosiloxanes GENERAL ELECTRIC COMPANY (US) 1985-12-10 US disclosed
EP-0138590-A2 Organosilicon compounds and preparation and use thereof Dow Corning Limited (GB) 1985-04-24 EP disclosed