Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | AHR | P35869 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19732837 | 0.88 | BRAF (0.64) | RAB9ASMN1; SMN2NPC1AHRMEN1 | |
| SCHEMBL11546092 | 0.87 | SMN1; SMN2 (0.68) | RAB9ASMN1; SMN2NPC1AHRMEN1 | |
| SCHEMBL2000945 | 0.86 | KMT2A (0.63) | RAB9ASMN1; SMN2NPC1AHRMEN1 | |
| SCHEMBL10264545 | 0.85 | SMN1; SMN2 (0.67) | RAB9ASMN1; SMN2NPC1AHRMEN1 | |
| SCHEMBL13978380 | 0.85 | RAB9A (0.67) | RAB9ASMN1; SMN2NPC1AHRMEN1 | |
| SCHEMBL4727210 | 0.84 | KMT2A (0.67) | RAB9ASMN1; SMN2NPC1AHRMEN1 | |
| SCHEMBL10755249 | 0.84 | NPC1 (0.74) | RAB9ASMN1; SMN2NPC1AHRMEN1 | |
| SCHEMBL3951459 | 0.83 | NPC1 (0.76) | RAB9ASMN1; SMN2NPC1AHRMEN1 | |
| SCHEMBL9969534 | 0.83 | SMN1; SMN2 (0.63) | RAB9ASMN1; SMN2NPC1AHRMEN1 | |
| SCHEMBL38660069 | 0.83 | SMN1; SMN2 (0.63) | RAB9ASMN1; SMN2NPC1AHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328968-B1 | PROCESS FOR THE PREPARATION OF 4-ACYLAMINO-2-AMINO ALKOXY BENZENES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-05-12 | — | — | EP | disclosed |
| US-5047586-A | Process for the preparation of 4-acylamino-2-aminoalkoxybenzenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-10 | — | — | US | disclosed |
| EP-0328968-A2 | Process for the preparation of 4-acylamino-2-amino alkoxy benzenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-23 | — | — | EP | disclosed |