Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504428 | 1.00 | ELANE (0.42) | ELANE | |
| SCHEMBL9506194 | 0.88 | ELANE (0.43) | ELANE | |
| SCHEMBL9506199 | 0.88 | ELANE (0.43) | ELANE | |
| SCHEMBL9503103 | 0.87 | HSD17B10 (0.52) | ELANE | |
| SCHEMBL9503094 | 0.87 | HSD17B10 (0.52) | ELANE | |
| SCHEMBL9503985 | 0.78 | MMP3 (0.44) | — | |
| SCHEMBL9503974 | 0.78 | MMP3 (0.44) | — | |
| SCHEMBL9503065 | 0.77 | TSHR (0.37) | — | |
| SCHEMBL9505017 | 0.76 | HSD17B10 (0.48) | ELANE | |
| SCHEMBL9505028 | 0.76 | HSD17B10 (0.48) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276436-B1 | PHOSPHINIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-06-16 | — | — | EP | disclosed |
| US-5006651-A | Rheumatic diseases, bone disorders | HOFFMAN-LA ROCHE INC. (US) | 1991-04-09 | — | — | US | disclosed |
| US-4885283-A | Phosphinic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1989-12-05 | — | — | US | disclosed |
| EP-0276436-A1 | Phosphinic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1988-08-03 | — | — | EP | disclosed |