Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26620702 | 0.83 | CYP2C19 (0.48) | ALDH1A1CYP1A2CYP2C19KCNA5KCNH2 | |
| SCHEMBL2681260 | 0.75 | TSHR (0.55) | ALDH1A1CYP1A2CYP2C19KCNA5KCNH2 | |
| SCHEMBL24316289 | 0.75 | CYP2C19 (0.46) | ALDH1A1CYP1A2CYP2C19KCNA5KCNH2 | |
| SCHEMBL21742145 | 0.72 | TSHR (0.51) | ALDH1A1CYP1A2CYP2C19KCNA5KCNH2 | |
| SCHEMBL2393894 | 0.72 | KDM4E (0.40) | ALDH1A1CYP1A2CYP2C19KCNA5KCNH2 | |
| SCHEMBL8626385 | 0.71 | ALDH1A1 (0.45) | ALDH1A1CYP1A2CYP2C19KCNA5KCNH2 | |
| SCHEMBL21742125 | 0.71 | KCNA5 (0.51) | ALDH1A1CYP1A2CYP2C19KCNA5KCNH2 | |
| SCHEMBL10694579 | 0.71 | CYP1A2 (0.43) | ALDH1A1CYP1A2CYP2C19SMN1; SMN2TSHR | |
| SCHEMBL14094773 | 0.70 | ALDH1A1 (0.49) | ALDH1A1CYP1A2CYP2C19KCNA5KCNH2 | |
| SCHEMBL2680153 | 0.69 | ALDH1A1 (0.55) | ALDH1A1CYP1A2CYP2C19KCNA5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426987-B1 | RAPIDLY IMMOBILIZING PAPER COATING COMPOSITIONS | National Starch and Chemical Investment Holding Corporation (US) | 1993-07-14 | — | — | EP | claimed |
| US-5093159-A | Cationic Starch, Pigment, Base | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1992-03-03 | — | — | US | claimed |
| EP-0426987-A1 | Rapidly immobilizing paper coating compositions | National Starch and Chemical Investment Holding Corporation (US) | 1991-05-15 | — | — | EP | claimed |
| EP-0426987-B1 | RAPIDLY IMMOBILIZING PAPER COATING COMPOSITIONS | National Starch and Chemical Investment Holding Corporation (US) | 1993-07-14 | — | — | EP | disclosed |
| US-5093159-A | Cationic Starch, Pigment, Base | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1992-03-03 | — | — | US | disclosed |
| EP-0426987-A1 | Rapidly immobilizing paper coating compositions | National Starch and Chemical Investment Holding Corporation (US) | 1991-05-15 | — | — | EP | disclosed |