Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | STAT6 | P42226 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17350556 | 0.75 | SMN1; SMN2 (0.49) | KDM4ECYP1A2TSHRLMNATRPM8 | |
| SCHEMBL31327941 | 0.75 | SMN1; SMN2 (0.49) | KDM4ECYP1A2TSHRLMNATRPM8 | |
| SCHEMBL26620702 | 0.73 | CYP2C19 (0.48) | KDM4ECYP1A2TSHRABCB11LMNA | |
| SCHEMBL9504585 | 0.72 | ALDH1A1 (0.46) | KDM4ECYP1A2TSHRABCB11LMNA | |
| SCHEMBL2681260 | 0.68 | TSHR (0.55) | CYP1A2TSHRLMNAADRA2ACYP2C9 | |
| SCHEMBL6666391 | 0.68 | TSHR (0.49) | KDM4ECYP1A2TSHRABCB11LMNA | |
| SCHEMBL24316289 | 0.68 | CYP2C19 (0.46) | KDM4ECYP1A2TSHRABCB11LMNA | |
| SCHEMBL16626907 | 0.68 | SMN1; SMN2 (0.59) | CYP1A2TSHRTRPM8SMN1; SMN2KMT2A | |
| SCHEMBL3957922 | 0.67 | TRPM8 (0.47) | KDM4ECYP1A2TSHRLMNAHIF1A | |
| SCHEMBL2187238 | 0.67 | L3MBTL1 (0.55) | KDM4ECYP1A2TSHRTRPM8SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110229410-A1 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | MOLECULAR INSIGHT PHARMACEUTICALS, INC. | 2011-09-22 | — | — | US | disclosed |
| US-20090023787-A1 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | MOLECULAR INSIGHT PHARMACEUTICALS, INC. | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110229410-A1 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | SLC7A5, SLC7A1, AADAT | KDM4E 1361/4885CYP1A2 4474/4885TSHR 41/4885 |
| US-20090023787-A1 | TECHNETIUM-DIPYRIDINE COMPLEXES, AND METHODS OF USE THEREOF | SLC7A5, SLC7A1, AADAT | KDM4E 1361/4885CYP1A2 4474/4885TSHR 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.