SCHEMBL9504639

SCHEMBL9504639

[CH2]CCCC(=O)NCCCCN(C)C

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.60
CASP2 P42575 1/20 0.43
PAOX Q6QHF9 1/20 0.42
KDM4E B2RXH2 2/20 0.42
TSHR P16473 2/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
NAAA Q02083 1/20 0.41
KDM4A O75164 6/20 0.39
HIF1A Q16665 1/20 0.39
TET2 Q6N021 1/20 0.39
DOHH Q9BU89 1/20 0.39
FAAH O00519 1/20 0.39
KDM4C Q9H3R0 5/20 0.38
KDM5A P29375 1/20 0.38
KDM7A Q6ZMT4 1/20 0.38
PHF8 Q9UPP1 1/20 0.38
KDM2A Q9Y2K7 1/20 0.38
DRD3 P35462 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9507721 0.95 DNM1 (0.67) DNM1CASP2PAOXKDM4ETSHR
SCHEMBL9504658 0.89 DNM1 (0.70) DNM1CASP2PAOXKDM4ETSHR
SCHEMBL8121890 0.85 DNM1 (0.59) DNM1CASP2PAOXTSHRKDM4A
SCHEMBL7137887 0.85 DNM1 (0.79) DNM1PAOXKDM4ETSHRNAAA
SCHEMBL23899001 0.83 DNM1 (0.82) DNM1CASP2PAOXKDM4ETSHR
SCHEMBL8773743 0.83 DNM1 (0.76) DNM1CASP2PAOXKDM4ETSHR
SCHEMBL1601857 0.81 DNM1 (0.90) DNM1CASP2NAAAFAAH
SCHEMBL16359464 0.81 DNM1 (0.68) DNM1CASP2PAOXKDM4ENAAA
SCHEMBL9549112 0.81 DNM1 (0.90) DNM1CASP2NAAAFAAH
SCHEMBL19479185 0.81 DNM1 (0.90) DNM1CASP2NAAAFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434354-B1 SEPARATION MATERIAL FOR BLOOD COAGULATION FACTOR, PREPARATION AND USE THEREOF KURITA WATER INDUSTRIES LTD. (JP) 1993-08-11 EP disclosed
EP-0434354-A1 Separation material for blood coagulation factor, preparation and use thereof KURITA WATER INDUSTRIES LTD. (JP) 1991-06-26 EP disclosed