SCHEMBL9504658

SCHEMBL9504658

[CH2]CCCCC(=O)NCCCN(C)C

nearest known ligand 0.70

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.70
PAOX Q6QHF9 1/20 0.46
KDM4E B2RXH2 2/20 0.44
FAAH O00519 3/20 0.42
TSHR P16473 3/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
NAAA Q02083 1/20 0.41
MAPT P10636 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
CASP2 P42575 1/20 0.39
ALOX15 P16050 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9507721 0.95 DNM1 (0.67) DNM1PAOXKDM4EFAAHTSHR
SCHEMBL23899001 0.91 DNM1 (0.82) DNM1PAOXKDM4EFAAHTSHR
SCHEMBL9504639 0.89 DNM1 (0.60) DNM1PAOXKDM4EFAAHTSHR
SCHEMBL7137887 0.89 DNM1 (0.79) DNM1PAOXKDM4EFAAHTSHR
SCHEMBL8773743 0.87 DNM1 (0.76) DNM1PAOXKDM4EFAAHTSHR
SCHEMBL8121890 0.85 DNM1 (0.59) DNM1PAOXFAAHTSHRSMN1; SMN2
SCHEMBL1527147 0.85 DNM1 (0.72) DNM1PAOXKDM4ETSHRNAAA
SCHEMBL8411584 0.84 DNM1 (0.72) DNM1PAOXKDM4EFAAHTSHR
SCHEMBL3319780 0.84 DNM1 (0.96) DNM1FAAHNAAACASP2
SCHEMBL27384481 0.84 DNM1 (0.72) DNM1PAOXKDM4EFAAHTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434354-B1 SEPARATION MATERIAL FOR BLOOD COAGULATION FACTOR, PREPARATION AND USE THEREOF KURITA WATER INDUSTRIES LTD. (JP) 1993-08-11 EP disclosed
EP-0434354-A1 Separation material for blood coagulation factor, preparation and use thereof KURITA WATER INDUSTRIES LTD. (JP) 1991-06-26 EP disclosed