Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.50 |
| ▸ | BID | P55957 | 3/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.47 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.47 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.47 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.45 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9508295 | 1.00 | LIPG (0.50) | LIPGBIDMCL1BCL2L1BAK1 | |
| SCHEMBL9504662 | 1.00 | LIPG (0.50) | LIPGBIDMCL1BCL2L1BAK1 | |
| SCHEMBL9506818 | 1.00 | LIPG (0.50) | LIPGBIDMCL1BCL2L1BAK1 | |
| SCHEMBL9506038 | 1.00 | LIPG (0.50) | LIPGBIDMCL1BCL2L1BAK1 | |
| SCHEMBL9506952 | 1.00 | LIPG (0.50) | LIPGBIDMCL1BCL2L1BAK1 | |
| SCHEMBL9508288 | 1.00 | LIPG (0.50) | LIPGBIDMCL1BCL2L1BAK1 | |
| SCHEMBL9508773 | 1.00 | LIPG (0.50) | LIPGBIDMCL1BCL2L1BAK1 | |
| SCHEMBL9504375 | 0.84 | ALOX5 (0.58) | BIDMCL1BCL2L1BAK1ALDH1A1 | |
| SCHEMBL11677461 | 0.84 | LIPG (0.46) | LIPGBIDMCL1BCL2L1BAK1 | |
| SCHEMBL7287500 | 0.83 | HCRTR1 (0.50) | LIPGBIDMCL1BCL2L1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | disclosed |
| CN-1012500-B | Process for preparing aryl hydroxamates | SQUIBB & SONS INC (US) | 1991-05-01 | — | — | CN | disclosed |
| CN-85104470-A | The method for preparing arythydroxamtes | — | 1986-10-01 | — | — | CN | disclosed |
| US-4607053-A | L2POXYGENASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | disclosed |
| EP-0161939-A2 | Arylhydroxamates | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | disclosed |