Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.51 |
| ▸ | PPARG | P37231 | 6/20 | 0.51 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.42 |
| ▸ | LPL | P06858 | 1/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9508869 | 0.89 | PPARA (0.52) | PPARAPPARGSPHK2SPHK1CYP4F2 | |
| SCHEMBL9504722 | 0.83 | PPARA (0.52) | PPARAPPARGSPHK2SPHK1LPL | |
| SCHEMBL15766204 | 0.79 | RARB (0.59) | PPARAPPARGLPLLIPG | |
| SCHEMBL15174619 | 0.79 | RARB (0.59) | PPARAPPARGLPLLIPG | |
| SCHEMBL27414335 | 0.79 | RARB (0.59) | PPARAPPARGLPLLIPG | |
| SCHEMBL11442846 | 0.79 | RARB (0.59) | PPARAPPARGLPLLIPG | |
| SCHEMBL1876486 | 0.79 | RARB (0.59) | PPARAPPARGLPLLIPG | |
| SCHEMBL289254 | 0.79 | RARB (0.59) | PPARAPPARGLPLLIPG | |
| SCHEMBL9504824 | 0.79 | THRA (0.50) | — | |
| SCHEMBL27284390 | 0.79 | PPARA (0.45) | PPARAPPARGSPHK2SPHK1CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | disclosed |
| CN-85104470-A | The method for preparing arythydroxamtes | — | 1986-10-01 | — | — | CN | disclosed |
| US-4607053-A | L2POXYGENASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | disclosed |
| EP-0161939-A2 | Arylhydroxamates | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | disclosed |