SCHEMBL9504882

SCHEMBL9504882

COC(C)(c1ccccc1C)c1ccccc1C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.45
GABRB2 P47870 1/20 0.45
TSHR P16473 2/20 0.41
ACHE P22303 2/20 0.41
ALDH1A1 P00352 4/20 0.39
TDP1 Q9NUW8 2/20 0.39
CA2 P00918 2/20 0.36
CASR P41180 1/20 0.35
CA1 P00915 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
ESR1 P03372 1/20 0.33
CYP3A4 P08684 1/20 0.32
ALOX5 P09917 1/20 0.32
GAA P10253 1/20 0.32
CYP1A2 P05177 3/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
NLRP3 Q96P20 1/20 0.31
CYP2A6 P11509 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9694912 0.87 MAPK1 (0.40) GABRA1GABRB2TSHRACHEALDH1A1
SCHEMBL9504908 0.83 TSHR (0.43) GABRA1GABRB2TSHRACHEALDH1A1
SCHEMBL9508330 0.81 TSHR (0.41) GABRA1GABRB2TSHRACHEALDH1A1
SCHEMBL11106181 0.81 TSHR (0.41) GABRA1GABRB2TSHRACHEALDH1A1
SCHEMBL30407772 0.79 GABRA1 (0.58) GABRA1GABRB2TSHRACHEALDH1A1
SCHEMBL5496813 0.79 GABRA1 (0.58) GABRA1GABRB2TSHRACHEALDH1A1
SCHEMBL542212 0.79 GABRA1 (0.58) GABRA1GABRB2TSHRACHEALDH1A1
SCHEMBL1316916 0.79 TSHR (0.39) GABRA1GABRB2TSHRACHEALDH1A1
SCHEMBL8784814 0.78 TSHR (0.43) GABRA1GABRB2TSHRACHEALDH1A1
SCHEMBL11429174 0.78 TSHR (0.43) GABRA1GABRB2TSHRACHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0261962-B1 PROCESS FOR PRODUCING PROPYLENE BLOCK COPOLYMER MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1993-07-28 EP disclosed