Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24113220 | 0.87 | MEN1 (0.41) | NPSR1MAPTKDM4EHPGDALDH1A1 | |
| SCHEMBL10722861 | 0.83 | NPSR1 (0.50) | NPSR1PKMMAPTKDM4EHPGD | |
| SCHEMBL22648611 | 0.82 | PARP1 (0.39) | MAPTKDM4EHPGDALDH1A1GAA | |
| SCHEMBL28344139 | 0.80 | NPSR1 (0.55) | NPSR1PKMMAPTKDM4EHPGD | |
| SCHEMBL1663646 | 0.79 | MAPT (0.54) | NPSR1PKMMAPTKDM4EHPGD | |
| SCHEMBL7045388 | 0.79 | NPSR1 (0.44) | NPSR1PKMMAPTKDM4EHPGD | |
| SCHEMBL9502744 | 0.79 | NPSR1 (0.53) | NPSR1PKMMAPTKDM4EHPGD | |
| SCHEMBL12145773 | 0.78 | NPSR1 (0.55) | NPSR1PKMMAPTKDM4EHPGD | |
| SCHEMBL15367263 | 0.77 | PKM (0.46) | NPSR1PKMMAPTKDM4EHPGD | |
| SCHEMBL1502530 | 0.77 | PARP1 (0.60) | NPSR1PKMHPGDALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186190-B1 | BENZIMIDAZOLE DERIVATIVES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-05-26 | — | — | EP | disclosed |
| US-4663339-A | Acaricidal and insecticidal substituted 1-phenylalkylbenzimidazoles | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-05-05 | — | — | US | disclosed |
| EP-0186190-A2 | Benzimidazole derivatives, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-07-02 | — | — | EP | disclosed |
| US-4000295-A | ARACHNICIDAL | ELI LILLY AND COMPANY (US) | 1976-12-28 | — | — | US | disclosed |