Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CD44 | P16070 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL470628 | 0.97 | GABRA1 (0.48) | GABRA1GABRB2TSHRACHECYP2A6 | |
| Water SCHEMBL2496499 | 0.95 | GABRA1 (0.46) | GABRA1GABRB2TSHRACHECYP2A6 | |
| Hydrochloric Acid SCHEMBL659883 | 0.95 | GABRA1 (0.46) | GABRA1GABRB2TSHRACHECYP2A6 | |
| Bromide SCHEMBL660019 | 0.95 | GABRA1 (0.46) | GABRA1GABRB2TSHRACHECYP2A6 | |
| Boric Acid SCHEMBL7183370 | 0.89 | GABRA1 (0.47) | GABRA1GABRB2TSHRACHECYP2A6 | |
| SCHEMBL7180493 | 0.89 | GABRA1 (0.47) | GABRA1GABRB2TSHRACHECYP2A6 | |
| Acetic Acid SCHEMBL9506298 | 0.85 | GABRA1 (0.44) | GABRA1GABRB2CYP1A2ALDH1A1CA2 | |
| Phosphoric Acid SCHEMBL7178344 | 0.85 | GABRA1 (0.44) | GABRA1GABRB2TSHRACHEALDH1A1 | |
| SCHEMBL11204082 | 0.82 | TSHR (0.45) | GABRA1GABRB2TSHRACHECYP2A6 | |
| Iodide SCHEMBL11522127 | 0.82 | TSHR (0.45) | GABRA1GABRB2TSHRACHECYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337322-B1 | PROCESS FOR PRODUCING MONOSILANE | MITSUBISHI KASEI CORPORATION (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-4904460-A | Process for producing monosilane | MITSUBISHI KASEI CORPORATION (JP) | 1990-02-27 | — | — | US | disclosed |
| EP-0337322-A2 | Process for producing monosilane | MITSUBISHI KASEI CORPORATION (JP) | 1989-10-18 | — | — | EP | disclosed |