Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501907 | 0.77 | SNCA (0.50) | SNCAMEN1KMT2ACYP3A4MAPT | |
| SCHEMBL461801 | 0.77 | SNCA (0.61) | SNCAMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL175786 | 0.75 | SNCA (0.67) | SNCAMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL9066444 | 0.75 | SNCA (0.52) | SNCAMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL9505777 | 0.74 | MAPT (0.41) | MEN1KMT2AMAPTRAB9AALDH1A1 | |
| SCHEMBL9505062 | 0.74 | SNCA (0.47) | SNCAMEN1KMT2ACYP3A4MAPT | |
| SCHEMBL9288915 | 0.72 | ADRB2 (0.55) | SNCAMEN1KMT2ACYP3A4MAPT | |
| SCHEMBL13563232 | 0.71 | MEN1 (0.51) | SNCAMEN1KMT2ACYP3A4MAPT | |
| SCHEMBL21063734 | 0.71 | MEN1 (0.51) | SNCAMEN1KMT2ACYP3A4MAPT | |
| SCHEMBL13563231 | 0.71 | MEN1 (0.51) | SNCAMEN1KMT2ACYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260077-B1 | PHENYL PYRIMIDINE COMPOUND AND LIQUID CRYSTALLINE COMPOSITION | AJINOMOTO CO., INC. (JP) | 1993-05-26 | — | — | EP | disclosed |
| EP-0244129-B1 | OPTICALLY ACTIVE COMPOUND AND LIQUID CRYSTALLINE COMPOSITION | AJINOMOTO CO., INC. (JP) | 1992-11-11 | — | — | EP | disclosed |
| US-4892676-A | FERROELECTRIC, HIGH SPEED RESPONSE | AJINOMOTO CO., INC. (JP) | 1990-01-09 | — | — | US | disclosed |
| US-4880561-A | Optically active compound and liquid crystalline composition | AJINOMOTO CO., INC. (JP) | 1989-11-14 | — | — | US | disclosed |