Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 16/20 | 0.62 |
| ▸ | MMP1 | P03956 | 2/20 | 0.58 |
| ▸ | MMP2 | P08253 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505069 | 1.00 | MMP3 (0.62) | MMP3MMP1MMP2 | |
| SCHEMBL9506219 | 0.91 | MMP3 (0.53) | MMP3MMP1MMP2 | |
| SCHEMBL9506211 | 0.91 | MMP3 (0.53) | MMP3MMP1MMP2 | |
| SCHEMBL9505195 | 0.86 | MMP3 (0.53) | MMP3MMP1MMP2 | |
| SCHEMBL9790672 | 0.83 | MMP3 (0.47) | MMP3MMP1MMP2 | |
| SCHEMBL9790680 | 0.83 | MMP3 (0.47) | MMP3MMP1MMP2 | |
| SCHEMBL9790825 | 0.82 | MMP3 (0.72) | MMP3MMP1 | |
| SCHEMBL9790838 | 0.82 | MMP3 (0.72) | MMP3MMP1 | |
| SCHEMBL27281835 | 0.81 | CTSL (0.52) | — | |
| SCHEMBL9504991 | 0.78 | MMP3 (0.45) | MMP3MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276436-B1 | PHOSPHINIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-06-16 | — | — | EP | disclosed |
| US-5006651-A | Rheumatic diseases, bone disorders | HOFFMAN-LA ROCHE INC. (US) | 1991-04-09 | — | — | US | disclosed |
| US-4885283-A | Phosphinic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1989-12-05 | — | — | US | disclosed |