Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.61 |
| ▸ | ANPEP | P15144 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 3/20 | 0.47 |
| ▸ | MMP3 | P08254 | 2/20 | 0.47 |
| ▸ | MMP7 | P09237 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5418223 | 1.00 | MMP2 (0.61) | MMP2ANPEPALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL5418227 | 1.00 | MMP2 (0.61) | MMP2ANPEPALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL17833288 | 1.00 | MMP2 (0.61) | MMP2ANPEPALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL2227030 | 0.88 | KMT2A (0.64) | MMP2ANPEPALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL21551113 | 0.88 | KMT2A (0.64) | MMP2ANPEPALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL8106846 | 0.88 | KMT2A (0.64) | MMP2ANPEPALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL1734641 | 0.87 | MMP2 (0.68) | MMP2ANPEPALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL1734643 | 0.87 | MMP2 (0.68) | MMP2ANPEPALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL8498279 | 0.87 | MMP1 (0.62) | MMP2ALDH1A1POLBMMP1MMP3 | |
| SCHEMBL8144145 | 0.87 | MMP1 (0.62) | MMP2ALDH1A1POLBMMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289911-B1 | PYRROLIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-16 | — | — | EP | disclosed |
| US-4916152-A | THROMBOXANE A2 ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-04-10 | — | — | US | disclosed |
| EP-0289911-A2 | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-09 | — | — | EP | disclosed |