Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.66 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.59 |
| ▸ | CCR3 | P51677 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28413750 | 0.85 | CNR2 (0.56) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL28414187 | 0.85 | ALDH1A1 (0.54) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL6813188 | 0.83 | ALDH1A1 (0.71) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL16889096 | 0.83 | ALDH1A1 (0.71) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL14350793 | 0.82 | ALDH1A1 (0.66) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL13647281 | 0.82 | ALDH1A1 (0.66) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL23316729 | 0.81 | RIPK1 (0.57) | SMN1; SMN2 | |
| SCHEMBL31034468 | 0.81 | RIPK1 (0.57) | SMN1; SMN2 | |
| SCHEMBL8652164 | 0.81 | RPS6KA5 (0.54) | ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6813768 | 0.81 | ALDH1A1 (0.69) | ALDH1A1HTTNCOA1SMN1; SMN2NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335374-B1 | N-[[(2,6-disubstituted)phenyl]-N'-diarylalkyl] ureas as antihyperlipidemic and antiatherosclerotic agents | WARNER-LAMBERT COMPANY (US) | 1993-06-30 | — | — | EP | claimed |
| EP-0335374-A2 | N-[[(2,6-disubstituted)phenyl]-N'-diarylalkyl] ureas as antihyperlipidemic and antiatherosclerotic agents | WARNER-LAMBERT COMPANY (US) | 1989-10-04 | — | — | EP | claimed |
| CN-114213286-A | Synthetic method of urea derivative | 湖北文理学院 | 2022-03-22 | — | — | CN | disclosed |
| EP-0335374-B1 | N-[[(2,6-disubstituted)phenyl]-N'-diarylalkyl] ureas as antihyperlipidemic and antiatherosclerotic agents | WARNER-LAMBERT COMPANY (US) | 1993-06-30 | — | — | EP | disclosed |
| EP-0335374-A2 | N-[[(2,6-disubstituted)phenyl]-N'-diarylalkyl] ureas as antihyperlipidemic and antiatherosclerotic agents | WARNER-LAMBERT COMPANY (US) | 1989-10-04 | — | — | EP | disclosed |