Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | TLR4 | O00206 | 1/20 | 0.30 |
| ▸ | TLR2 | O60603 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3302854 | 0.80 | ALDH1A1 (0.37) | ALDH1A1CYP3A4NPC1MAPTRAB9A | |
| SCHEMBL3296812 | 0.79 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL2967255 | 0.79 | — | — | |
| SCHEMBL14778239 | 0.78 | — | — | |
| SCHEMBL115527 | 0.75 | LMNA (0.47) | ALDH1A1CYP3A4DNM1ADRB2ADRB1 | |
| SCHEMBL3305110 | 0.74 | TSHR (0.35) | ALDH1A1CYP3A4NPC1MAPTRAB9A | |
| SCHEMBL4056511 | 0.74 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL3668650 | 0.73 | MEN1 (0.38) | ALDH1A1 | |
| SCHEMBL11059065 | 0.73 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL30539136 | 0.73 | LMNA (0.45) | ALDH1A1CYP3A4DNM1ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129995-B2 | A PROCESS FOR THE MANUFACTURE OF NITRIC ACID ESTERS | AECI LIMITED (ZA) | 1993-09-08 | — | — | EP | disclosed |
| US-4853157-A | Process for the manufacture of nitric acid esters | AECI LIMITED (ZA) | 1989-08-01 | — | — | US | disclosed |
| EP-0129995-B1 | A PROCESS FOR THE MANUFACTURE OF NITRIC ACID ESTERS | AECI LIMITED (ZA) | 1987-05-13 | — | — | EP | disclosed |
| EP-0129995-A2 | A process for the manufacture of nitric acid esters | AECI LIMITED (ZA) | 1985-01-02 | — | — | EP | disclosed |