Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15131195 | 0.91 | EPHX2 (0.66) | EPHX2SIGMAR1EPHX1KMT2AMEN1 | |
| SCHEMBL15131218 | 0.91 | EPHX2 (0.66) | EPHX2SIGMAR1EPHX1KMT2AMEN1 | |
| SCHEMBL8907879 | 0.83 | EPHX2 (0.50) | EPHX2SIGMAR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23023176 | 0.83 | EPHX2 (0.50) | EPHX2SIGMAR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9390747 | 0.81 | SIGMAR1 (0.50) | EPHX2SIGMAR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4971804 | 0.79 | SIGMAR1 (0.63) | EPHX2SIGMAR1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL17604761 | 0.78 | SIGMAR1 (0.50) | EPHX2SIGMAR1SMN1; SMN2EPHX1ALDH1A1 | |
| SCHEMBL17605508 | 0.78 | SIGMAR1 (0.50) | EPHX2SIGMAR1SMN1; SMN2EPHX1ALDH1A1 | |
| SCHEMBL17605316 | 0.78 | SIGMAR1 (0.50) | EPHX2SIGMAR1SMN1; SMN2EPHX1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL17605202 | 0.77 | SIGMAR1 (0.49) | EPHX2SIGMAR1RAB9ASMN1; SMN2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540576-A1 | PSYCHOACTIVE DRUG AND TREATMENT | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1993-05-12 | — | — | EP | claimed |
| WO-1992001449-A1 | PSYCHOACTIVE DRUG AND TREATMENT | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1992-02-06 | — | — | WO | claimed |
| CN-116635508-A | Alkaline ashless additive and lubricating composition containing the same | 路博润公司 | 2023-08-22 | — | — | CN | disclosed |
| EP-0540576-A1 | PSYCHOACTIVE DRUG AND TREATMENT | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1993-05-12 | — | — | EP | disclosed |