SCHEMBL9505558

SCHEMBL9505558

NCC[C@H]1CC[C@@H](C(=O)O)CC1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.68
PLG P00747 1/20 0.68
PLAT P00750 1/20 0.68
ANPEP P15144 2/20 0.48
ENPEP Q07075 1/20 0.48
GABRP O00591 1/20 0.39
GABRD O14764 1/20 0.39
GABRA1 P14867 1/20 0.39
TSHR P16473 1/20 0.39
GABRB1 P18505 1/20 0.39
GABRG2 P18507 1/20 0.39
GABRB3 P28472 1/20 0.39
GABRA5 P31644 1/20 0.39
GABRA3 P34903 1/20 0.39
GABRA2 P47869 1/20 0.39
GABRB2 P47870 1/20 0.39
GABRA4 P48169 1/20 0.39
GABRE P78334 1/20 0.39
PMP22 Q01453 1/20 0.39
GABRA6 Q16445 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3501690 1.00 LMNA (0.68) LMNAPLGPLATANPEPENPEP
SCHEMBL3501688 1.00 LMNA (0.68) LMNAPLGPLATANPEPENPEP
Hydrochloric Acid SCHEMBL7328494 0.98 LMNA (0.65) LMNAPLGPLATANPEPENPEP
SCHEMBL9294046 0.92 LMNA (0.59) LMNAPLGPLATANPEPENPEP
SCHEMBL9506256 0.87 PLG (0.57) LMNAPLGPLATANPEPENPEP
SCHEMBL11664391 0.85 LMNA (0.65) LMNAPLGPLATANPEPENPEP
SCHEMBL850864 0.84 LMNA (0.64) LMNAPLGPLATANPEPENPEP
SCHEMBL9293095 0.84 LMNA (0.59) LMNAPLGPLATANPEPENPEP
SCHEMBL8897842 0.82 LMNA (0.45) LMNAPLGPLATANPEPENPEP
Tranexamic Acid SCHEMBL186034 0.81 PLG (1.00) LMNAPLGPLATANPEPENPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0329105-B1 MOLECULAR WEIGHT CONTROLLER FOR POLYMERIZATION OF LACTAMS TO POLYAMIDES BASF Corporation (US) 1993-07-07 EP claimed
US-5006635-A Monofunctional amine, monofunctional acid, salt of aminoacid, polyamides BASF CORPORATION (US) 1991-04-09 US claimed
EP-0329105-A2 Molecular weight controller for polymerization of lactams to polyamides BASF Corporation (US) 1989-08-23 EP claimed
EP-0329105-B1 MOLECULAR WEIGHT CONTROLLER FOR POLYMERIZATION OF LACTAMS TO POLYAMIDES BASF Corporation (US) 1993-07-07 EP disclosed
US-5006635-A Monofunctional amine, monofunctional acid, salt of aminoacid, polyamides BASF CORPORATION (US) 1991-04-09 US disclosed
US-4844834-A Molecular weight controller for polymerization of lactams to polyamides BASF CORPORATION (US) 1989-07-04 US disclosed