Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tranexamic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG known ✓ | P00747 | 1/20 | 1.00 |
| ▸ | PLAT | P00750 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | ANPEP | P15144 | 1/20 | 0.52 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tranexamic Acid SCHEMBL16974 | 1.00 | PLG (1.00) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL423790 | 1.00 | PLG (1.00) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL349408 | 1.00 | PLG (1.00) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL322487 | 1.00 | PLG (1.00) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL19031783 | 0.98 | PLG (0.95) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL3793503 | 0.98 | PLG (0.95) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL11189660 | 0.98 | PLG (0.95) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL10723480 | 0.98 | PLG (0.95) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL7326280 | 0.98 | PLG (0.95) | PLGPLATLMNAANPEPENPEP | |
| Tranexamic Acid SCHEMBL29236634 | 0.98 | PLG (0.95) | PLGPLATLMNAANPEPENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4426 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260115253-A1 | VISCOUS COMPOSITION FOR TREATING ISCHEMIA | UNIV NAT CHENG KUNG (TW) | 2026-04-30 | — | — | US | claimed |
| US-20260108481-A1 | COMPOUNDS FOR PREVENTION AND TREATMENT OF HEMORRHAGE AND VASCULATURE INSTABILITY | ABREXA PHARMACEUTICALS INC (US) | 2026-04-23 | — | — | US | claimed |
| EP-3619231-B1 | TRUNCATED VWF | IMPERIAL COLLEGE INNOVATIONS LTD (GB) | 2026-01-28 | — | — | EP | claimed |
| US-20260007571-A1 | PHARMACEUTICAL CONTAINER WITH PH PROTECTIVE LAYER DEPOSITED BY ATOMIC LAYER DEPOSITION | INNOVATIVE SCIENTIFIC PRODUCTS, INC. (US) | 2026-01-08 | — | — | US | claimed |
| US-12516006-B2 | Recycle content propanol | ExxonMobil Product Solutions Company (US) | 2026-01-06 | — | — | US | claimed |
| US-20260002181-A1 | METHOD FOR PRODUCING 4-(AMINOMETHYL)CYCLOHEXANE-1-CARBOXYLIC ACID | KIRIN HOLDINGS KABUSHIKI KAISHA (JP) | 2026-01-01 | — | — | US | claimed |
| WO-2025262265-A1 | CHIMERIC MOLECULES COMPRISING AN ANTI-FIBRIN ANTIBODY AND AN ANTITHROMBOTIC MOLECULE | ETABLISSEMENT FRANCAIS DU SANG (FR) | 2025-12-26 | — | — | WO | claimed |
| US-20250382291-A1 | SUBSTITUTED PYRROLO[2,3-b]PYRIDINES FOR SUPPRESSING TOXIC ENDOPLASMIC RETICULUM STRESS | UNIV COLUMBIA (US) | 2025-12-18 | — | — | US | claimed |
| US-12497349-B2 | Salts of tranexamic acid esters | Actera Ingredients, Inc. (US) | 2025-12-16 | — | — | US | claimed |
| US-12496281-B2 | Compounds for prevention and treatment of hemorrhage and vasculature instability | ABREXA PHARMACEUTICALS, INC. (US) | 2025-12-16 | — | — | US | claimed |
| EP-0055145-A1 | 4-(Aminomethyl)cyclohexane-1-carboxylic acid derivatives | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1982-06-30 | — | — | EP | claimed |
| EP-0041826-A2 | 4-(N-(substituted-benzylidene)aminomethyl)cyclohexane-1-carboxylic acids | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1981-12-16 | — | — | EP | claimed |
| EP-0041827-A2 | A N-(benzylidene) aminomethyl-cyclohexane-carboxylic acid | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1981-12-16 | — | — | EP | claimed |
| US-RE30149-E | OXIDATION OF 4-AMINOMETHYL-CYCLOHEXANE METHANOL | AB KABI (SE) | 1979-11-13 | — | — | US | claimed |
| US-4071553-A | Method for the production of trans-4-aminomethyl cyclohexane-1-carboxylic acid | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1978-01-31 | — | — | US | claimed |
| US-4048222-A | P-AMINOMETHYLBENZOIC ACID, RUTHENIUM CATALYST | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) | 1977-09-13 | — | — | US | claimed |
| US-3998947-A | Process for obtaining a plasminogen activator | PIERRE FABRE S.A. (FR) | 1976-12-21 | — | — | US | claimed |
| US-3959253-A | β-D-glucosyluronic acid derivatives | MERCK & CO., INC. (US) | 1976-05-25 | — | — | US | claimed |
| US-3956503-A | 4-AMINOMETHYL-CYCLOHEXANECARBOXYLIC ACID | DAIICHI SEIYAKU CO., LTD. (JA) | 1976-05-11 | — | — | US | claimed |
| US-3950405-A | ANTIPLASMIN AGENTS | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1976-04-13 | — | — | US | claimed |