SCHEMBL9505642

SCHEMBL9505642

CC(=O)Oc1ccc(Oc2ccc(OC(C)=O)cc2C)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.55
ACHE P22303 1/20 0.51
KDM4E B2RXH2 4/20 0.49
KMT2A Q03164 2/20 0.48
GAA P10253 3/20 0.46
GLA P06280 2/20 0.46
MAPT P10636 4/20 0.46
POLB P06746 1/20 0.46
PKM P14618 1/20 0.46
ALDH1A1 P00352 2/20 0.45
CYP3A4 P08684 2/20 0.45
MEN1 O00255 1/20 0.45
TTR P02766 1/20 0.45
TP53 P04637 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
ELANE P08246 1/20 0.44
MAPK1 P28482 1/20 0.44
HSD17B10 Q99714 1/20 0.43
TSHR P16473 1/20 0.43
NFKB1 P19838 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9760614 0.95 LMNA (0.53) LMNAACHEKDM4EKMT2AGAA
SCHEMBL11577550 0.93 ACHE (0.54) LMNAACHEKDM4EKMT2AGAA
SCHEMBL29535063 0.87 KDM4E (0.58) LMNAACHEKDM4EKMT2AGAA
SCHEMBL2541390 0.87 KDM4E (0.58) LMNAACHEKDM4EKMT2AGAA
SCHEMBL1490220 0.87 ACHE (0.46) LMNAACHEKDM4EKMT2AGAA
SCHEMBL14700586 0.86 KMT2A (0.49) LMNAACHEKDM4EKMT2AGAA
SCHEMBL3326684 0.84 ACHE (0.53) LMNAACHEKDM4EKMT2AGAA
SCHEMBL10449007 0.80 MAPT (0.50) LMNAACHEKDM4EKMT2AMAPT
SCHEMBL31086822 0.80 MAPT (0.50) LMNAACHEKDM4EKMT2AMAPT
SCHEMBL5338819 0.80 HTT (0.45) LMNAACHEKDM4EKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0212482-B1 PROCESS FOR OBTAINING NEGATIVE IMAGES FROM POSITIVE PHOTORESISTS HOECHST CELANESE CORPORATION (US) 1989-04-19 EP claimed
EP-0311387-B1 AROMATIC AMINE RESINS, THEIR PRODUCTION PROCESS AND THERMOSETTING RESIN COMPOSITIONS MAKING USE OF THE SAME MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-08-11 EP disclosed
EP-0342943-B1 THERMOSETTING RESIN COMPOSITION MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-08-04 EP disclosed
US-5145949-A Production process for making aromatic amine resins MITSUI TOATSU CHEMICALS, INC. (JP) 1992-09-08 US disclosed
US-5122442-A Water soluble binder; photosensitive compound HOECHST CELANESE CORPORATION (US) 1992-06-16 US disclosed
US-5106953-A Reacting aromatic amines with bishalogenomethyl derivatives; curing agents or raw materials for polyamides MITSUI TOATSU CHEMICALS, INC. (JP) 1992-04-21 US disclosed
US-5051494-A A bismaleimide and an amino resin MITSUI TOATSU CHEMICALS, INC. (JP) 1991-09-24 US disclosed
US-4959443-A HIGH STRENGTH, REACTION OF ARALKYL ALCOHOL AND AROMATIC AMINE MITSUI TOATSU CHEMICALS, INC. (JP) 1990-09-25 US disclosed
US-4937318-A Aromatic amine resins MITSUI TOATSU CHEMICALS, INC. (JP) 1990-06-26 US disclosed
EP-0342943-A1 Thermosetting resin composition MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-11-23 EP disclosed
EP-0212482-B1 PROCESS FOR OBTAINING NEGATIVE IMAGES FROM POSITIVE PHOTORESISTS HOECHST CELANESE CORPORATION (US) 1989-04-19 EP disclosed
EP-0106156-B1 LIGHT-SENSITIVE COMPOSITION HOECHST CELANESE CORPORATION (US) 1988-12-21 EP disclosed
EP-0212482-A2 Process for obtaining negative images from positive photoresists HOECHST CELANESE CORPORATION (US) 1987-03-04 EP disclosed
EP-0061150-B1 LIGHT-SENSITIVE POLYCONDENSATION PRODUCT, PROCESS FOR ITS PREPARATION AND LIGHT-SENSITIVE RECORDING MATERIAL CONTAINING THE SAME AMERICAN HOECHST CORPORATION (US) 1986-10-15 EP disclosed
EP-0098982-B1 PHOTOPOLYMERIZABLE MIXTURE, AND PHOTOPOLYMERIZABLE COPYING MATERIAL PRODUCED THEREWITH HOECHST AKTIENGESELLSCHAFT (DE) 1986-08-06 EP disclosed
US-4458006-A PRINTING PLATES HOECHST AKTIENGESELLSCHAFT (DE) 1984-07-03 US disclosed
EP-0106156-A2 Light-sensitive composition HOECHST CELANESE CORPORATION (US) 1984-04-25 EP disclosed
EP-0098982-A1 Photopolymerizable mixture, and photopolymerizable copying material produced therewith HOECHST AKTIENGESELLSCHAFT (DE) 1984-01-25 EP disclosed
EP-0061150-A1 Light-sensitive polycondensation product, process for its preparation and light-sensitive recording material containing the same AMERICAN HOECHST CORPORATION (US) 1982-09-29 EP disclosed