Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.62 |
| ▸ | PLK1 | P53350 | 4/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503257 | 0.92 | ACAT1 (0.60) | ACAT1PLK1NR1H4LMNAMAPT | |
| SCHEMBL9365128 | 0.87 | ACAT1 (0.71) | ACAT1PLK1NR1H4TP53TSHR | |
| SCHEMBL9366147 | 0.86 | ACAT1 (0.83) | ACAT1PLK1NR1H4MAPTMAPK1 | |
| SCHEMBL9366207 | 0.86 | ACAT1 (0.83) | ACAT1PLK1NR1H4MAPTMAPK1 | |
| SCHEMBL9361223 | 0.86 | ACAT1 (0.83) | ACAT1PLK1NR1H4MAPTMAPK1 | |
| SCHEMBL9503247 | 0.85 | ACAT1 (0.76) | ACAT1PLK1NR1H4LMNAMAPT | |
| SCHEMBL9503223 | 0.84 | PLK1 (0.58) | ACAT1PLK1NR1H4LMNAMAPT | |
| SCHEMBL9502459 | 0.83 | ACAT1 (0.72) | ACAT1PLK1NR1H4LMNAMAPT | |
| SCHEMBL9362304 | 0.82 | ACAT1 (0.74) | ACAT1PLK1NR1H4LMNAMAPT | |
| SCHEMBL9502352 | 0.82 | ACAT1 (0.77) | ACAT1PLK1NR1H4LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992003408-A1 | BENZANILIDE DERIVATIVES AND THEIR USE AS ANTI-ANTHEROSCLEROTIC AGENTS | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | claimed |
| EP-0543884-A1 | BENZANILIDE DERIVATIVES AND THEIR USE AS ANTI-ATHEROSCLEROTIC AGENTS | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003408-A1 | BENZANILIDE DERIVATIVES AND THEIR USE AS ANTI-ANTHEROSCLEROTIC AGENTS | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |