Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.76 |
| ▸ | PLK1 | P53350 | 4/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502459 | 0.95 | ACAT1 (0.72) | ACAT1PLK1NR1H4TP53TSHR | |
| SCHEMBL9502352 | 0.93 | ACAT1 (0.77) | ACAT1PLK1NR1H4TP53TSHR | |
| SCHEMBL9504200 | 0.91 | ACAT1 (0.67) | ACAT1PLK1NR1H4TP53TSHR | |
| SCHEMBL9502479 | 0.90 | ACAT1 (0.80) | ACAT1PLK1NR1H4TP53TSHR | |
| SCHEMBL9505673 | 0.89 | ACAT1 (0.67) | ACAT1PLK1NR1H4TP53TSHR | |
| SCHEMBL9361187 | 0.86 | ACAT1 (1.00) | ACAT1PLK1NR1H4MAPTMAPK1 | |
| SCHEMBL9361027 | 0.86 | ACAT1 (1.00) | ACAT1PLK1NR1H4MAPTMAPK1 | |
| SCHEMBL6940849 | 0.86 | ACAT1 (1.00) | ACAT1PLK1NR1H4MAPTMAPK1 | |
| SCHEMBL9365235 | 0.86 | ACAT1 (1.00) | ACAT1PLK1NR1H4MAPTMAPK1 | |
| SCHEMBL9361036 | 0.86 | ACAT1 (1.00) | ACAT1PLK1NR1H4MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543884-A1 | BENZANILIDE DERIVATIVES AND THEIR USE AS ANTI-ATHEROSCLEROTIC AGENTS | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | claimed |
| WO-1992003408-A1 | BENZANILIDE DERIVATIVES AND THEIR USE AS ANTI-ANTHEROSCLEROTIC AGENTS | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | claimed |
| EP-0543884-A1 | BENZANILIDE DERIVATIVES AND THEIR USE AS ANTI-ATHEROSCLEROTIC AGENTS | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003408-A1 | BENZANILIDE DERIVATIVES AND THEIR USE AS ANTI-ANTHEROSCLEROTIC AGENTS | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |