Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | BHMT | Q93088 | 4/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL9502012 | 0.83 | CYP1A2 (0.43) | ITGB3ITGA2BLMNASMN1; SMN2CYP1A2 | |
| SCHEMBL467886 | 0.81 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPK1CHRM5CHRM3BLM | |
| SCHEMBL5865021 | 0.78 | CYP1A2 (0.57) | ITGB3ITGA2BLMNASMN1; SMN2CYP1A2 | |
| SCHEMBL27793739 | 0.78 | CYP1A2 (0.57) | ITGB3ITGA2BLMNASMN1; SMN2CYP1A2 | |
| Adipic Acid SCHEMBL8962598 | 0.77 | CYP1A2 (0.47) | ITGB3ITGA2BLMNASMN1; SMN2CYP1A2 | |
| Adipic Acid SCHEMBL8433509 | 0.77 | CYP1A2 (0.47) | ITGB3ITGA2BLMNASMN1; SMN2CYP1A2 | |
| SCHEMBL9154884 | 0.77 | CYP1A2 (0.55) | ITGB3ITGA2BLMNASMN1; SMN2CYP1A2 | |
| SCHEMBL11429662 | 0.77 | CYP1A2 (0.55) | ITGB3ITGA2BLMNASMN1; SMN2CYP1A2 | |
| SCHEMBL21727957 | 0.77 | CYP1A2 (0.55) | ITGB3ITGA2BLMNASMN1; SMN2CYP1A2 | |
| Hydrochloric Acid SCHEMBL27810605 | 0.77 | CYP1A2 (0.55) | ITGB3ITGA2BLMNASMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0348063-B1 | THERMOPLASTIC ELASTOMER AND PHOTOSENSITIVE RESIN COMPOSITION BASED THEREON, AND PRINTING PLATE PRECURSOR COMPRISING THE COMPOSITION | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1993-05-26 | — | — | EP | disclosed |
| US-5053316-A | THERMOPLASTIC ELASTOMER AND PHOTOSENSITIVE RESIN COMPOSITION BASED THEREON, AND PRINTING PLATE PRECURSOR COMPRISING THE COMPOSITION | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1991-10-01 | — | — | US | disclosed |
| EP-0348063-A1 | Thermoplastic elastomer and photosensitive resin composition based thereon, and printing plate precursor comprising the composition | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1989-12-27 | — | — | EP | disclosed |