Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.39 |
| ▸ | BHMT | Q93088 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GRM8 | O00222 | 1/20 | 0.36 |
| ▸ | GRM6 | O15303 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL9505699 | 0.83 | ITGB3 (0.43) | CYP1A2MAPK1SMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL27793739 | 0.83 | CYP1A2 (0.57) | CYP1A2MAPK1SMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL5865021 | 0.83 | CYP1A2 (0.57) | CYP1A2MAPK1SMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL1469940 | 0.82 | POLB (0.45) | SMN1; SMN2ANPEPERAP2CXCR4 | |
| Adipic Acid SCHEMBL8433509 | 0.81 | CYP1A2 (0.47) | CYP1A2MAPK1SMN1; SMN2ITGB3ITGA2B | |
| Adipic Acid SCHEMBL8962598 | 0.81 | CYP1A2 (0.47) | CYP1A2MAPK1SMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL9154884 | 0.81 | CYP1A2 (0.55) | CYP1A2MAPK1SMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL21727957 | 0.81 | CYP1A2 (0.55) | CYP1A2MAPK1SMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL11429662 | 0.81 | CYP1A2 (0.55) | CYP1A2MAPK1SMN1; SMN2ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL27810605 | 0.81 | CYP1A2 (0.55) | CYP1A2MAPK1SMN1; SMN2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0348063-B1 | THERMOPLASTIC ELASTOMER AND PHOTOSENSITIVE RESIN COMPOSITION BASED THEREON, AND PRINTING PLATE PRECURSOR COMPRISING THE COMPOSITION | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1993-05-26 | — | — | EP | disclosed |
| US-5053316-A | THERMOPLASTIC ELASTOMER AND PHOTOSENSITIVE RESIN COMPOSITION BASED THEREON, AND PRINTING PLATE PRECURSOR COMPRISING THE COMPOSITION | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1991-10-01 | — | — | US | disclosed |
| EP-0348063-A1 | Thermoplastic elastomer and photosensitive resin composition based thereon, and printing plate precursor comprising the composition | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1989-12-27 | — | — | EP | disclosed |