Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 8/20 | 0.50 |
| ▸ | MAOA | P21397 | 4/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6165864 | 0.84 | ALDH1A1 (0.78) | ALDH1A1MAPK1NPC1RAB9AMAOB | |
| SCHEMBL921629 | 0.83 | ALDH1A1 (0.68) | ALDH1A1MAPK1NPC1RAB9AMAOB | |
| Hydrochloric Acid SCHEMBL6158469 | 0.82 | ALDH1A1 (0.66) | ALDH1A1MAPK1NPC1RAB9AMAOB | |
| SCHEMBL29642903 | 0.80 | TAAR1 (0.60) | ALDH1A1TAAR1CYP3A4SLC6A4CYP1A2 | |
| SCHEMBL50478 | 0.80 | TAAR1 (0.60) | ALDH1A1TAAR1CYP3A4SLC6A4CYP1A2 | |
| SCHEMBL18415547 | 0.79 | ALDH1A1 (0.71) | ALDH1A1MAPK1NPC1RAB9AMAOB | |
| Methylene Chloride SCHEMBL29186228 | 0.78 | TAAR1 (0.58) | ALDH1A1TAAR1CYP3A4SLC6A4CYP1A2 | |
| Methane SCHEMBL27598295 | 0.78 | TAAR1 (0.58) | ALDH1A1TAAR1CYP3A4SLC6A4CYP1A2 | |
| SCHEMBL7799758 | 0.78 | MAPK1 (0.51) | ALDH1A1MAPK1NPC1RAB9AMAOB | |
| SCHEMBL8993266 | 0.77 | TAAR1 (0.53) | TAAR1CYP3A4SLC6A4CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186190-B1 | BENZIMIDAZOLE DERIVATIVES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-05-26 | — | — | EP | disclosed |
| EP-0132606-B1 | BENZIMIDAZOLE DERIVATIVES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-10-07 | — | — | EP | disclosed |
| US-4663339-A | Acaricidal and insecticidal substituted 1-phenylalkylbenzimidazoles | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-05-05 | — | — | US | disclosed |
| US-4612323-A | Insecticidal and acaricidal derivatives of 1-benzylbenzimidazole | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-09-16 | — | — | US | disclosed |
| EP-0186190-A2 | Benzimidazole derivatives, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-07-02 | — | — | EP | disclosed |
| EP-0132606-A1 | Benzimidazole derivatives, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-02-13 | — | — | EP | disclosed |