Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2417808 | 0.94 | LMNA (0.53) | LTA4HLMNAL3MBTL1ALDH1A1HTT | |
| SCHEMBL9503567 | 0.92 | LTA4H (0.63) | LTA4HALDH1A1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL9503541 | 0.89 | LTA4H (0.66) | LTA4HTSHRMEN1KMT2A | |
| SCHEMBL9505726 | 0.87 | ACACB (0.49) | LTA4HALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL2995440 | 0.86 | TSHR (0.56) | LTA4HALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL9723672 | 0.85 | LTA4H (0.79) | LTA4HLMNAL3MBTL1CA12CA1 | |
| SCHEMBL6158908 | 0.84 | LTA4H (0.61) | LTA4HLMNAALDH1A1CA12CA1 | |
| SCHEMBL9502090 | 0.84 | LMNA (0.45) | LTA4HLMNAL3MBTL1ALDH1A1HTT | |
| SCHEMBL6018241 | 0.82 | NR5A1 (0.58) | LTA4HTSHRMEN1KMT2A | |
| SCHEMBL9705907 | 0.81 | HRH3 (0.42) | LTA4HTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186190-B1 | BENZIMIDAZOLE DERIVATIVES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-05-26 | — | — | EP | disclosed |
| EP-0132606-B1 | BENZIMIDAZOLE DERIVATIVES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-10-07 | — | — | EP | disclosed |
| US-4663339-A | Acaricidal and insecticidal substituted 1-phenylalkylbenzimidazoles | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-05-05 | — | — | US | disclosed |
| US-4612323-A | Insecticidal and acaricidal derivatives of 1-benzylbenzimidazole | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-09-16 | — | — | US | disclosed |
| EP-0186190-A2 | Benzimidazole derivatives, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-07-02 | — | — | EP | disclosed |
| EP-0132606-A1 | Benzimidazole derivatives, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-02-13 | — | — | EP | disclosed |