Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502837 | 0.93 | DHODH (0.85) | DHODHPDE10A | |
| SCHEMBL10582007 | 0.89 | DHODH (0.77) | DHODHPDE10A | |
| SCHEMBL10582434 | 0.88 | DHODH (1.00) | DHODHPDE10A | |
| SCHEMBL7686140 | 0.88 | DHODH (0.79) | DHODHPDE10A | |
| SCHEMBL9503660 | 0.85 | DHODH (0.78) | DHODHPDE10A | |
| SCHEMBL17594005 | 0.85 | DHODH (0.94) | DHODHPDE10A | |
| SCHEMBL9502210 | 0.84 | DHODH (1.00) | DHODHPDE10A | |
| SCHEMBL9505334 | 0.83 | DHODH (0.77) | DHODHPDE10A | |
| SCHEMBL9501979 | 0.83 | DHODH (1.00) | DHODHPDE10A | |
| SCHEMBL19351185 | 0.82 | DHODH (0.71) | DHODHPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0305952-B1 | SUBSTITUTED 2-PHENYL-4-QUINOLINE-CARBOXYLIC ACIDS | AMERICAN CYANAMID COMPANY (US) | 1993-06-02 | — | — | EP | disclosed |
| US-4847381-A | ANTIARTHRITIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| EP-0305952-A1 | Substituted 2-phenyl-4-quinoline-carboxylic acids | AMERICAN CYANAMID COMPANY (US) | 1989-03-08 | — | — | EP | disclosed |