SCHEMBL9506029

SCHEMBL9506029

Nc1ccc(Oc2ccc(Oc3ccc(S(=O)(=O)O)cc3)cc2)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.75
TSHR P16473 5/20 0.75
NT5E P21589 1/20 0.75
TDP1 Q9NUW8 3/20 0.58
CYP3A4 P08684 2/20 0.58
HTT P42858 2/20 0.54
PARP10 Q53GL7 1/20 0.52
MMP2 P08253 4/20 0.50
MMP9 P14780 4/20 0.50
MAOA P21397 2/20 0.50
MMP3 P08254 1/20 0.50
MMP8 P22894 1/20 0.50
MMP14 P50281 1/20 0.50
MAPT P10636 4/20 0.48
LMNA P02545 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
NPC1 O15118 1/20 0.48
TP53 P04637 1/20 0.48
XBP1 P17861 1/20 0.48
MAPK1 P28482 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23581821 1.00 ALDH1A1 (0.75) ALDH1A1TSHRNT5ETDP1CYP3A4
Sulfuric Acid SCHEMBL8640279 0.98 ALDH1A1 (0.72) ALDH1A1TSHRNT5ETDP1CYP3A4
SCHEMBL6090901 0.89 ALDH1A1 (0.58) ALDH1A1TSHRNT5ETDP1HTT
SCHEMBL9249636 0.89 ALDH1A1 (0.58) ALDH1A1TSHRNT5ETDP1HTT
SCHEMBL28521152 0.87 ALDH1A1 (0.56) ALDH1A1TSHRNT5ETDP1HTT
Sulfuric Acid SCHEMBL8647113 0.87 ALDH1A1 (0.70) ALDH1A1TSHRNT5ETDP1CYP3A4
Sulfuric Acid SCHEMBL8644562 0.87 ALDH1A1 (0.70) ALDH1A1TSHRNT5ETDP1CYP3A4
SCHEMBL482994 0.87 TSHR (1.00) ALDH1A1TSHRNT5ETDP1CYP3A4
SCHEMBL30495973 0.87 TSHR (1.00) ALDH1A1TSHRNT5ETDP1CYP3A4
SCHEMBL24407 0.87 TSHR (1.00) ALDH1A1TSHRNT5ETDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5001146-A None JP disclosed
JP-H051146-A POLYAMIDE RESIN AND ITS COMPOSITION MITSUI TOATSU CHEM INC 1993-01-08 JP disclosed