Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 4/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10385192 | 0.99 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL9503890 | 0.88 | USP2 (0.39) | ALDH1A1MEN1KMT2AHRH1HTR1A | |
| Hydrochloric Acid SCHEMBL9758874 | 0.87 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AHRH1HTR1A | |
| Hydrochloric Acid SCHEMBL9758866 | 0.87 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AHRH1HTR1A | |
| Hydrochloric Acid SCHEMBL10385724 | 0.86 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2AHRH1HTR1A | |
| SCHEMBL10385689 | 0.81 | ACHE (0.41) | ALDH1A1MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL9332052 | 0.80 | HDAC3 (0.47) | ALDH1A1MEN1KMT2AHRH1HTR1A | |
| Hydrochloric Acid SCHEMBL10385194 | 0.80 | HRH1 (0.54) | ALDH1A1MEN1KMT2ACYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL9759596 | 0.79 | HDAC3 (0.47) | ALDH1A1MEN1KMT2AHRH1HTR1A | |
| Hydrochloric Acid SCHEMBL9759597 | 0.79 | HDAC3 (0.47) | ALDH1A1MEN1KMT2AHRH1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346240-B1 | PHENOTHIAZINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RHONE-POULENC SANTE (FR) | 1993-06-02 | — | — | EP | claimed |
| US-4912105-A | Derivatives of phenothiazine and the compositions which contain them | RHONE-POULENC SANTE (FR) | 1990-03-27 | — | — | US | claimed |
| US-4912105-A | Derivatives of phenothiazine and the compositions which contain them | RHONE-POULENC SANTE (FR) | 1990-03-27 | — | — | US | disclosed |