Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 2/20 | 0.51 |
| ▸ | TTR | P02766 | 3/20 | 0.50 |
| ▸ | UNG | P13051 | 1/20 | 0.49 |
| ▸ | FBP1 | P09467 | 1/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.47 |
| ▸ | F7 | P08709 | 3/20 | 0.47 |
| ▸ | F3 | P13726 | 3/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ECE1 | P42892 | 1/20 | 0.47 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.47 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.47 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | P4HB | P07237 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504789 | 1.00 | STS (0.51) | STSTTRUNGFBP1CYSLTR2 | |
| SCHEMBL9504784 | 1.00 | STS (0.51) | STSTTRUNGFBP1CYSLTR2 | |
| SCHEMBL290446 | 0.94 | TTR (0.53) | STSTTRUNGFBP1P4HB | |
| SCHEMBL2817107 | 0.94 | TTR (0.53) | STSTTRUNGFBP1P4HB | |
| SCHEMBL290447 | 0.94 | TTR (0.53) | STSTTRUNGFBP1P4HB | |
| Acetic Acid SCHEMBL11384341 | 0.91 | TTR (0.50) | STSTTRUNGFBP1P4HB | |
| SCHEMBL18759142 | 0.89 | PPARA (0.43) | STSF7F3MMP2KDM4E | |
| SCHEMBL27557941 | 0.87 | PPARA (0.40) | STSTTRF7F3MMP2 | |
| SCHEMBL11340084 | 0.86 | UNG (0.52) | TTRUNGFBP1P4HB | |
| SCHEMBL27690332 | 0.85 | P4HB (0.51) | P4HB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | disclosed |
| CN-85104470-A | The method for preparing arythydroxamtes | — | 1986-10-01 | — | — | CN | disclosed |
| US-4607053-A | L2POXYGENASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | disclosed |
| EP-0161939-A2 | Arylhydroxamates | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | disclosed |