Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GLB1 | P16278 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CTRC | Q99895 | 1/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504813 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TSHRSMAD3THRBRECQL | |
| SCHEMBL8649408 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TSHRSMAD3THRBRECQL | |
| SCHEMBL9502985 | 0.69 | SMAD3 (0.37) | ALDH1A1TSHRSMAD3THRBRECQL | |
| SCHEMBL9503676 | 0.65 | SMAD3 (0.34) | ALDH1A1TSHRSMAD3THRBRECQL | |
| SCHEMBL22342647 | 0.63 | — | — | |
| SCHEMBL21861 | 0.59 | TSHR (1.00) | ALDH1A1TSHRSMAD3TDP1HIF1A | |
| SCHEMBL30354042 | 0.59 | TSHR (1.00) | ALDH1A1TSHRSMAD3TDP1HIF1A | |
| SCHEMBL11881041 | 0.59 | ALDH1A1 (0.44) | ALDH1A1TSHRCYP3A4HPGDHSD17B10 | |
| SCHEMBL8995862 | 0.57 | TSHR (0.82) | ALDH1A1TSHRTDP1HIF1AHSD17B10 | |
| SCHEMBL11669424 | 0.56 | ALDH1A1 (0.41) | ALDH1A1TSHRCYP3A4HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377406-B1 | PRESSURE-SENSITIVE OR HEAT-SENSITIVE RECORDING MATERIAL | CIBA-GEIGY AG (CH) | 1993-06-09 | — | — | EP | disclosed |
| US-5013707-A | Pressure- or heat-sensitive recording material | CIBA-GEIGY CORPORATION (US) | 1991-05-07 | — | — | US | disclosed |
| EP-0377406-A1 | Pressure-sensitive or heat-sensitive recording material | CIBA-GEIGY AG (CH) | 1990-07-11 | — | — | EP | disclosed |