Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171941 | 0.86 | NPC1 (0.72) | NPC1RAB9ARECQLTDP1SMN1; SMN2 | |
| SCHEMBL26132980 | 0.83 | RAB9A (0.57) | NPC1RAB9ARECQLTDP1SMN1; SMN2 | |
| SCHEMBL8489668 | 0.82 | NPC1 (0.56) | NPC1RAB9ARECQLTDP1SMN1; SMN2 | |
| SCHEMBL10263950 | 0.82 | NPC1 (0.56) | NPC1RAB9ARECQLTDP1SMN1; SMN2 | |
| SCHEMBL310065 | 0.82 | NPC1 (0.56) | NPC1RAB9ARECQLTDP1SMN1; SMN2 | |
| SCHEMBL28436127 | 0.81 | NPC1 (0.54) | NPC1RAB9ARECQLTDP1SMN1; SMN2 | |
| SCHEMBL30072726 | 0.80 | TDP1 (0.60) | NPC1RAB9ARECQLTDP1SMN1; SMN2 | |
| SCHEMBL1141627 | 0.80 | TDP1 (0.60) | NPC1RAB9ARECQLTDP1SMN1; SMN2 | |
| SCHEMBL310951 | 0.79 | KDM4E (0.55) | NPC1RAB9ARECQLTDP1SMN1; SMN2 | |
| SCHEMBL1616773 | 0.78 | TDP1 (0.58) | NPC1RAB9ARECQLTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279096-B1 | BENZYL ETHER COMPOUND AND PROCESS FOR PRODUCING THE SAME | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1993-07-07 | — | — | EP | claimed |
| CN-1023223-C | Process for preparing 1, 5-diphenyl-1H-1, 2, 4-triazole-3-carboxamide derivatives | KUREHA CHEMICAL IND CO LTD (JP) | 1993-12-22 | — | — | CN | disclosed |
| US-4919707-A | Derivative of 1,5-diphenyl-1H-1,2,4-triazole-3-carboxamide and herbicidal composition containing the same | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-04-24 | — | — | US | disclosed |
| CN-87102978-A | 1, 5-diphenyl-1H-1, 2, 4-triazole-3-carboxamide derivatives and herbicidal formulations thereof | — | 1988-10-05 | — | — | CN | disclosed |